The Biology I Course was developed through the Ohio Department of Higher Education OER Innovation Grant. The course is part of the Ohio Transfer Assurance Guides and is also named OSC003. This work was completed and the course was posted in October 2019. For more information about credit transfer between Ohio colleges and universities, please visit: www.ohiohighered.org/transfer.Team LeadCathy Sistilli                                         Eastern Gateway Community CollegeContent ContributorsLisa Aschemeier                                 Northwest State Community CollegeShaun Blevins                                     Rhodes State CollegeRachel Detraz                                     Edison State Community College                                     Sara Finch                                          Sinclair Community CollegeWendy Gagliano                                 Clark State Community College AJ Snow                                             University of Akron Wayne CollegeLibrarianAmanda Rinehart                               Ohio State UniversityReview TeamJessica Hall                                        Ohio Dominican UniversitySanhita Gupta                                    Kent State UniversityErica Mersfelder                                 Sinclair Community College

People did not understand the mechanisms of inheritance, or genetics, at the time Charles Darwin and Alfred Russel Wallace were developing their idea of natural selection. Scholars rediscovered Mendel’s work in the early twentieth century, and over the next few decades scientists integrated genetics and evolution in what became known as the modern synthesis—the coherent understanding of the relationship between natural selection and genetics that took shape by the 1940s. Natural selection can affect a population’s genetic makeup, and, in turn, this can result in the gradual evolution of populations. In the early twentieth century, biologists in the area of population genetics began to study how selective forces change a population through changes in allele and genotypic frequencies.  Adaptive evolution is the process by which natural selection increases the frequency of beneficial alleles in the population, while decreasing the frequency of deleterious alleles.

An integrated course stressing the principles of biology. Life processes are examined primarily at the organismal and population levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

This course presents a unique and challenging perspective on the causes of human disease and mortality. The course focuses on analyses of major causes of mortality in the US since 1900: cancer cardiovascular and cerebrovascular diseases, diabetes, infectious diseases. Students create analytical models to derive estimates for historically variant population risk factors and physiological rate parameters, and conduct analyses of familial data to separately estimate inherited and environmental risks. The course evaluates the basic population genetics of dominant, recessive and non-deleterious inherited risk factors.

Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts.