Chemistry is the study of matter. Our understanding of chemical processes thus depends on our ability to acquire accurate information about matter. Often, this information is quantitative, in the form of measurements. In this lab, you will be introduced to some common measuring devices, and learn how to use them to obtain correct measurements, each with correct precision. A metric ruler will be used to measure length in centimeters (cm).
Advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry illustrated through molecular spectroscopy. Instruction and practice in the written and oral presentation of experimental results.
This seminar will be a scientific exploration of the food we eat and enjoy. Each week we shall have a scientific edible experiment that will explore a specific food topic. Topics include, but are not limited to, what makes a good experiment, cheese making, joys of tofu, food biochemistry, the science of spice, what is taste?
Application of structure and theory to the study of organic reaction mechanisms: stereochemical features including conformation and stereoelectronic effects; reaction dynamics, isotope effects and molecular orbital theory applied to pericyclic and photochemical reactions; and special reactive intermediates including carbenes, carbanions, and free radicals.
12.491 is a seminar focusing on problems of current interest in geology and geochemistry. For Fall 2005, the topic is organic geochemistry. Lectures and readings cover recent research in the development and properties of organic matter.
These courses, produced by the Massachusetts Institute of Technology, introduce the fundamental concepts and approaches of aerospace engineering, highlighted through lectures on aeronautics, astronautics, and design. MIT˘ďď_s Aerospace and Aeronautics curriculum is divided into three parts: Aerospace information engineering, Aerospace systems engineering, and Aerospace vehicles engineering. Visitors to this site will find undergraduate and graduate courses to fit all three of these areas, from Exploring Sea, Space, & Earth: Fundamentals of Engineering Design to Bio-Inspired Structures
This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work will culminate in the preparation of a unique grant application in an area of biological networks.
Analytical chemistry spans nearly all areas of chemistry but involves the development of tools and methods to measure physical properties of substances and apply those techniques to the identification of their presence (qualitative analysis) and quantify the amount present (quantitative analysis) of species in a wide variety of settings.
Analytical chemistry is more than a collection of analytical methods and an understanding of equilibrium chemistry; it is an approach to solving chemical problems. Although equilibrium chemistry and analytical methods are important, their coverage should not come at the expense of other equally important topics. The introductory course in analytical chemistry is the ideal place in the undergraduate chemistry curriculum for exploring topics such as experimental design, sampling, calibration strategies, standardization, optimization, statistics, and the validation of experimental results. Analytical methods come and go, but best practices for designing and validating analytical methods are universal. Because chemistry is an experimental science it is essential that all chemistry students understand the importance of making good measurements.
As currently taught in the United States, introductory courses in analytical chemistryemphasize quantitative (and sometimes qualitative) methods of analysis along with a heavydose of equilibrium chemistry. Analytical chemistry, however, is much more than a collection ofanalytical methods and an understanding of equilibrium chemistry; it is an approach to solvingchemical problems. Although equilibrium chemistry and analytical methods are important, theircoverage should not come at the expense of other equally important topics.
The introductory course in analytical chemistry is the ideal place in the undergraduate chemistry curriculum forexploring topics such as experimental design, sampling, calibration strategies, standardization,optimization, statistics, and the validation of experimental results. Analytical methods comeand go, but best practices for designing and validating analytical methods are universal. Becausechemistry is an experimental science it is essential that all chemistry students understand theimportance of making good measurements.
My goal in preparing this textbook is to find a more appropriate balance between theoryand practice, between “classical” and “modern” analytical methods, between analyzing samplesand collecting samples and preparing them for analysis, and between analytical methods anddata analysis. There is more material here than anyone can cover in one semester; it is myhope that the diversity of topics will meet the needs of different instructors, while, perhaps,suggesting some new topics to cover.
This course details the quantitative treatment of chemical processes in aquatic systems such as lakes, oceans, rivers, estuaries, groundwaters, and wastewaters. It includes a brief review of chemical thermodynamics that is followed by discussion of acid-base, precipitation-dissolution, coordination, and reduction-oxidation reactions. Emphasis is on equilibrium calculations as a tool for understanding the variables that govern the chemical composition of aquatic systems and the fate of inorganic pollutants.
This course provides an introduction to the physics and chemistry of the atmosphere, including experience with computer codes. It is intended for undergraduates and first year graduate students.
This is a free textbook offered by Saylor Foundation. The Basics of General, Organic, and Biological Chemistry by David W. Ball, John W. Hill, and Rhonda J. Scott is a new textbook offering for the one-semester GOB Chemistry course. The authors designed this book from the ground up to meet the needs of a one-semester course. It is 20 chapters in length and approximately 350-400 pages; just the right breadth and depth for instructors to teach and students to grasp. In addition, The Basics of General, Organic, and Biological Chemistry is written not by one chemist, but THREE chemistry professors with specific, complimentary research and teaching areas. David W. Ball’s specialty is physical chemistry, John W. Hill’s is organic chemistry, and finally, Rhonda J. Scott’s background is in enzyme and peptide chemistry. These three authors have the expertise to identify and present only the most important material for students to learn in the GOB Chemistry course.
This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.
This is an introductory course in biochemistry, designed for both biology and chemical engineering majors.
A consistent theme in this course is the development of a quantitative understanding of the interactions of biological molecules from a structural, thermodynamic, and molecular dynamic point of view. A molecular simulation environment provides the opportunity for you to explore the effect of molecular interactions on the biochemical properties of systems. Topics covered include: Protein Function, Structure and Function of Carbohydrates, Lipids and Biological Membranes, Metabolism, Nucleic and Acid and Biochemistry.
" The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format. Acknowledgments Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan."
Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.
" This course is designed for advanced undergraduate and graduate students with an interest in using primary research literature to discuss and learn about current research around sulfur biogeochemistry and astrobiology."
Chemical Biology research uses the tools of chemistry and synthesis to understand biology and disease pathways at the molecular level. Advanced Biological Chemistry interests include diverse topics such as nucleic acids, DNA repair, bioconjugate chemistry, peptides and peptidomimetics, glycoscience, biomolecular structure and function, imaging, and biological catalysis. Biophysical Chemistry represents the union of Chemistry, Physics, and Biology using a variety of experimental and theoretical approaches to understand the structure and function of biological systems.
This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication. The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.